Thursday 21 December 2017

Cannabis and Mental Health: Cause, Cure, or It’s Complicated? (Yes)

Elianna Lev

(Amy Phung at Leafly)
 
As the countdown to legal Canadian cannabis ticks forward, there’s growing interest in cannabis’s medical potential when it comes to mental illness, something that affects one in five Canadians.


Are those with mental illness using cannabis to help with symptoms, or are they using it as a result of having a mental illness?
 
Given those stats, and the reality that, outside of tobacco and alcohol, cannabis is the most common psychoactive substance used among the general population, it’s inevitable that the potential overlap of cannabis and mental illness will lead to a spike in questions for doctors.

And yet, many patients share a similar experience: When they approach their doctors about the possibility of using cannabis to help with mental illness, the suggestion is strongly dismissed.

Since cannabis has a long way to go before it shakes off the stigma of being an illicit drug, some perceive it as a chicken-or-egg conundrum among those who use it to treat mental illness. Are those with mental illness using it to help with symptoms, or are they using it as a result of having a mental illness?

Because research into this quandary is minimal and doctors are often unforthcoming, the evidence is largely anecdotal.

Toronto-based photographer and activist Andy Lee uses cannabis, along with talk therapy, to treat his depression and anxiety. He came to this balance after trying antidepressants, and deciding they weren’t effective for him.

Since his doctor made it clear he was against the idea of medicinal cannabis to treat mental illness, Lee found another practitioner who was comfortable prescribing it. “I know this is a touchy subject and taboo but this worked,” he says.

Lee is now involved in cannabis and mental health advocacy.

“I know this is a touchy subject but this worked.” 
 
Andy Lee on treating his depression with cannabis
Even though he’s found treatment that works, he admits there are risks to overusing cannabis. “It’s a healing plant but it shouldn’t be abused and taken for granted,” he says. “It’s like antibiotics, the positive effects diminish the more your body gets used to it.”

Claire Gabereau relates. For years, the Vancouver-based costume designer would chronically smoke cannabis. When she was diagnosed with depression, anxiety, and borderline personality disorder, her doctor strongly discouraged her from consuming cannabis. Her psychiatrist, on the other hand, was more open-minded and never criticized Gabereau’s habits. But when an additional diagnosis determined she had substance-use disorder, she decided to go completely sober, rather than start antidepressants.

“I didn’t like [that my psychiatrist] was like ‘sobriety might be good for you, here’s a bunch of drugs,’” she says.

It’s been three months since Gabereau changed her habits and her depression and anxiety appear to have subsided. “I don’t want to go back to smoking it all the time because I’d definitely get paranoia and anxiety,” she says. “It can be used as a tool and medicine but since I’ve been abusing it for so long, it lost its value and purpose.”

Invaluable Research from Israel

Most scientists will agree that cannabis’s 100+ compounds, known as cannabinoids, have a clear effect on humans’ biology. But there are a lot of gaps in the research of the therapeutic role it can play when it comes to mental illness, especially in the US, where medical research is stifled by cannabis’s prohibitive designation as a schedule-I narcotic.
Shauli Lev-Ran (courtesy of the subject)
Shauli Lev-Ran  is an addiction psychiatrist based in Tel Aviv. He focuses on the psychiatric aspects of cannabis use and the interface between pain, psychiatric disorders, and risk of addition.

He regularly treats patients in his clinical practice with both psychiatric disorders and cannabis-use disorders. As legislation and regulations surrounding cannabis change across the US, Canada, and other countries, he started examining the connection between mental health and cannabis more deeply.

Despite his area of expertise, Lev-Ran admits he hasn’t found definitive answers when it comes to the chicken-or-egg theory of what comes first, mental illness or the dependency on cannabis. “It’s complex and there are a lot of methodical issues that confound our ability to get reasonable answers to these questions,” he says.

In 2013, Lev-Ran conducted a study through the Centre for Mental Health and Addictions in Toronto.

Based on data collected by the National Institute for Alcoholism Abuse and Alcoholism, it was a cross-sectional study of more than 43,000 people—the largest epidemiological study on psychiatric disorders and substance use abuse. Lev-Ran found people with mental illnesses are over seven times more likely to use cannabis weekly than those without a mental illness.

More specifically, the study analyzed the difference between the rates of cannabis use and abuse amongst people with psychiatric disorders compared to those without. The research was based on the subjects’ number and types of psychiatric disorders and the intensity of their cannabis use, which Lev-Ran admits is challenging to quantify. Unlike alcohol, there are no standard doses with cannabis use.

Lev-Ran found people with mental illnesses are over seven times more likely to use cannabis weekly than those without a mental illness.
 
“We can talk about frequency and we can talk about dose, but they’re not standardized,” he says. “If I smoke two joints a day that are low in THC, it’s one thing, but if I smoke skunk or high potency and I smoke a large joint without tobacco as a filler, in both cases the dose seems like the same but they’re very different.”

Lev-Ran followed up with a meta-analysis, culled from thousands of existing studies, and found that those who use cannabis are at an increased risk for developing depression. However, he noticed many of the individual studies within the meta-analysis left out significant considerations, such as childhood upbringing and a family history of substance abuse.

Lev-Ran followed up with another study in 2016, which surveyed both cannabis users and non-users who had never suffered from depression. It set to understand if cannabis users who never experienced depression were at higher risk of suffering from an onset of the mental illness, compared to non-users. The study also analyzed data from the National Institute for Alcoholism Abuse and Alcoholism. This time, it followed up on 34,000 individuals who had taken part in the 2013 study.

Lev-Ran found that regardless of frequency (or infrequency) of use of cannabis, there was no difference between the rates of depression. Conversely, individuals with depression were at a higher risk to start using cannabis compared to those with no depression.

“One thing is to maybe say that cannabis isn’t very detrimental but it also shows that it isn’t very helpful.”
Shauli Lev-Ran 
 
Next, Lev-Ran examined if cannabis works in favour for those with depression. He surveyed people with mental illness who used cannabis and those who didn’t and found very little difference between the two groups. It’s a conclusion that can be interpreted in two ways.

“One thing is to maybe say that cannabis isn’t very detrimental but it also shows that it isn’t very helpful,” he says, adding that the conclusion was only based on one study. “But this shows the line on how we explore these questions.”

What makes researching cannabis and its effect on mental illness challenging is that cannabis isn’t an all-encompassing substance. There are thousands of strains and hundreds of chemical compounds like cannabinoids and terpenes within the plant.

“It’s clear that we’re not talking about one uniform compound,” he says. “So lumping all cannabis users together is almost ridiculous.”

The research on psychotic disorders like bipolar or schizophrenia is more clear-cut. The consensus is that cannabis triggers such disorders and can lead to substantially worse outcomes. But risk for any disease or disorder is a combination of pre-disposition and exposure to risk factors. For people heritably predisposed to schizophrenia, using cannabis, particularly during adolescence, increases the risk of developing the mental illness.

PTSD Leads the Way

Zach Walsh spends a lot of time examining the ties between marijuana consumption, mental health, and addiction. As an associate professor of psychology at the University of British Columbia, he oversees the Therapeutic, Recreational, and Problematic Substance Use lab, which studies cannabis use for therapeutic and recreational purposes.

Walsh says the only way to really know if mental illness precedes cannabis use or the other way around would be to follow people from an early age. That’s because most people start using cannabis around the same time they would demonstrate signs of mental illness—in their mid to late teens.

Walsh says the strongest evidence from his lab on cannabis’ effectiveness is among patients who suffer from post-traumatic stress disorder.
 
“Say you started smoking at 14 and at 18 are diagnosed with depression. It’d be hard to say whether you were feeling little bits of depression and were dealing with it by smoking cannabis as a pre-depression syndrome,” he says.

Medical trials can help reveal whether people who have mental illnesses are better off using cannabis or not, but researchers are far from understanding much beyond that.

Walsh points to the stigma around cannabis, which is still illegal in most countries, and how it hinders the drug’s potential from being taken seriously as medicine. Since cannabis has been branded an illegal substance that’s often associated with criminality, people don’t associate it with relief from symptoms. That could take time to reverse.

“I think [cannabis] should be given a balanced assessment,” he says. “All [drugs] have risks and relative benefits. We just have this stigma around cannabis. We’re less critical of drugs that come from pharmaceutical.”

Walsh says the strongest evidence from his lab on cannabis’ effectiveness is among patients who suffer from post-traumatic stress disorder, particularly in reducing nightmares. This is especially relevant for Canada’s Department of Veterans Affairs (VAC) and the Department of National Defense (DND), which are also reviewing existing research on the use cannabis for medical purposes. VAC will cover the costs of medicinal cannabis—to a limit of three grams a day—for some veterans who suffer from PTSD.

In a statement to Leafly, a Veterans Affairs official wrote: “Recognizing that this is still an emerging practice and field of study, the Department wants to ensure that the specific direction of its research initiative undertaken with DND will have the greatest impact on strengthening evidence on the effects of marijuana on the health of Veterans.”

“All (drugs) have risks and relative benefits. We just have this stigma around cannabis. We’re less critical of drugs that come from pharmaceutical.”
researcher Zach Walsh
 
Walsh suspects that future trials will focus on broader anxiety disorders, which are often treated with pharmaceuticals like Valium or Ativan.

“It’s worth looking at side by side because those drugs have side effects as well,” he says. “They can lead to tolerance and withdrawal.”

If patients with mental illnesses or anxiety disorders are going to try cannabis as a treatment, Walsh stresses the importance of self-reporting. Finding a strain that works could be likened to finding the right prescription and dosage if a patient were to go on anti-depressants or anti-anxiety medication.

Sometimes it takes a few months of trial and error to find the medicine that helps. By closely monitoring how certain strains and doses feel, a patient will get a better sense of what’s effective and what isn’t.

“As adults we should be given the choice,” he says. “The harms of cannabis have been well-tested even if the benefits haven’t been. I think adults can go in and make sufficient choices about whether they want to use cannabis or not.”

You Can’t Argue with Results

Toronto resident Alexandra Charendoff fully agrees, despite regularly being discouraged from cannabis use by a number of health care practitioners. After being  diagnosed with borderline personality disorder, generalized anxiety disorder, and agoraphobia, Charendoff found cannabis was the most powerful and effective way to relieve the anxiety that paralyzed her when she had to leave the house.

“It was almost instantaneous,” she says. “I can actually function when I smoke weed. It’s the only thing that’s had any impact. When I take an Ativan, I just want to lie down and sleep.”

When she brought up the possibility with her doctor, “it was apparent he’d had this conversation multiple times before” but wasn’t in favour of going the medicinal-marijuana route. She wasn’t that surprised. Every time she’d been to the ER for treatment for an episode, doctors strongly railed against cannabis use, but never had any data to back up why. Charendoff felt their input was one-sided.

“They’ll say it’s not a good idea but there’s no room for conversation,” Charendoff says.

It’s likely the data on marijuana’s potential to treat symptoms of mental illness will spike once the drug is legalized in Canada, and more research is administered. Until then, doctors will continue fielding question about how cannabis can potentially help. If they don’t have answers, it’s likely that patients, like Lee and Charendoff, will continue to explore options themselves.

“I don’t think it’s going to cure my mental illness,” says Charendoff. “But it helps.”

Simulator aims to help police test whether a person is too high to drive

By CBS News

The new year will mark the official start of recreational marijuana sales in California, and there are fears it could lead to more impaired driving. Among U.S. drivers killed in crashes who tested positive for drugs, more than a third in 2015 had used marijuana.

At the University of California San Diego, researchers are trying to help police detect whether a person is too high to get behind the wheel.

"Part of this study, we wanted to get at memory issues," said Tom Marcotte, co-director for the university's Center for Medicinal Cannabis Research.

When you drive on Marcotte's simulator, he's not checking how good a driver you are – but how bad a driver you may become high on pot.
 
"The idea of the off ramp is actually something that the police suggested to you," CBS News correspondent Barry Petersen said.

"Because in their estimation, that's one of the areas that are most difficult for impaired drivers to handle," Marcotte responded.
 
The real test subjects light up, some with a real joint, others with a placebo. Then they are put through the simulator challenges like deciding whether it's safe to drive through a yellow light. They also face a multi-tasking test: finding the right circle.

It's all designed to eventually create a tool, perhaps a tablet test, that police can use roadside to determine if someone is too stoned to drive.
 "The ultimate outcome is to see whether or not we can really help law enforcement separate those people who are impaired due to cannabis or those people who may have cannabis in their system and are not impaired," Marcotte said.
 
Unlike alcohol, there is no accepted marijuana breathalyzer. Blood tests can be inconclusive depending on when the test is taken. To make it more complicated, pot affects different people differently. 

"There are indications that the more experienced you are, the more tolerance you develop," Marcotte said.

"So a person who smokes a lot might actually have less effect when it comes to driving?" Petersen asked.

"That's correct. Because their body is adjusted to it, they know what to expect," Marcotte said.

California Highway Patrol's Sgt. Glen Glaser Jr. teaches officers how to recognize a driver under the influence.


"How much does this end up making a kind of a judgment call, if that's the right word?" Petersen asked.

"Well, I think it very much is a judgment call because we want our officers only arresting people who are impaired," Glaser said.
 
Right now officers mostly rely on subjective observations like walking the line and "is there a pot smell in the car?"


While a lot of Californians are looking forward to January 1 when recreational marijuana goes on sale, Glaser and police across the state are braced. 

"The big scare is going to be those people who are going to try for the first time come January 1 and not knowing how it affects their body," Glaser said.
 
One day, the simulator may lead to an answer and help catch someone impaired by pot before getting too high gets someone hurt.

Pivot Pharma Signs Binding Letter of Intent to Acquire Cannabis Oil Infusion Technology for Use in Food and Beverage Products

Source: Pivot Pharmaceuticals Inc.
 
VANCOUVER, British Columbia, Dec. 20, 2017 (GLOBE NEWSWIRE) -- Pivot Pharmaceuticals Inc. (CSE:PVOT) (OTCQB:PVOTF) (“Pivot” or the “Company”), an emerging biopharmaceutical company, is pleased to announce that the Company has signed a Binding Letter of Intent to acquire ERS Holdings, LLC (“ERS”), a privately-held California company. ERS has developed a patented technology called “RTIC” - Ready To Infuse Cannabis (“the Patent”) and has also filed several continuation patents relating to the transformation of cannabis oil into powder for infusion into a variety of food and beverage products such as capsules, K-Cups, stick packs, baked mixes, liquid shots, protein shakes, topicals, lotions and bottled beverages.

In exchange for 100% of ERS (Patent Portfolio and Trademarks for “Instant THC™” and “Instant CBD™”), Pivot will pay ERS $1,000,000 USD and 5,000,000 Common Shares (“The Shares”) of Pivot Pharmaceuticals Inc. The Shares will be subject to a six (6) month restriction with the first 25% of the total number of Shares to be released six (6) months following the closing date, with 25% to be released every quarter thereafter. Completion of the acquisition is subject to regulatory approval and standard closing conditions.

A recent report by Deloitte suggests that “on sales of recreational marijuana alone, the Canadian marketplace could be as much as $5B per year to start – a number on par with the Canadian spirit market (whiskey, vodka, rum, etc.). At the upper threshold, which takes into account the people who are 'likely to consume,' marijuana sales alone could be as high as $8.7B, similar to sales generated by wine.”

Current cannabis product formulations are either poorly absorbed topicals and orals or inhaled and smoked carcinogens. Health-conscious adults who seek the therapeutic benefits of cannabis without the negative health effects represent a large, untapped demographic. This demographic is also inundated with edible product choices that are high in sugar, such as candy or confectionary. Health-seeking consumers who use cannabis daily represent a large market opportunity for Pivot. The acquisition of ERS allows Pivot to add to its growing pipeline of cannabis-based products.

Invented by Ross Franklin and Ed Rosenthal, the invention “relates generally to methods and compositions of matter for enabling concentrated cannabis oil to be stable, emulsifiable and flavorless for use in hot beverages or food by combining cannabis oil with a starch powder or starch-derived powder.  Embodiments also relate to a variety of culinary uses for the stabilized, emulsified, flavorless concentrated cannabis oil powder.”

Mr. Franklin, ERS’ CEO, said, “After being courted by some of Canada’s largest cannabis companies, we selected the Pivot team to help monetize our patent. Their management team has extensive pharmaceutical and nutraceutical industry experience and an impressive track record of bringing products to market.  In addition to the food and beverage markets, we also look forward to integrating 'RTIC' into Pivot’s current topical, oral and nanoparticulate pipeline.”

Dr. Patrick Frankham, CEO of Pivot Pharmaceuticals, stated, “Pivot believes that the anticipated changes in cannabis regulation in Canada and California will provide an opportunity to launch multiple products into the healthcare and recreational markets in 2018. We are delighted that Ross Franklin and Pat Rolfes from ERS have chosen Pivot to help transform their patents and processes into therapeutic consumer goods. Pivot is in ongoing discussions with several Canadian Licensed Producers and Licensed Dealers in order to accelerate commercialization of our large pipeline of technology-driven products. If a suitable joint venture partner is not identified by January 2018, Pivot will seek a Licensed Dealer designation from Health Canada and commence construction of its own production facility. As a result, Pivot has engaged CBRE, the world’s largest commercial real estate firm, to help facilitate the site selection process.”

Grandmother throws out ‘all her pills’ and says cannabis is the key



Ever sat and wondered what the secret to a long and healthy life is?

Well wonder no more, because one grandmother reckons that she has the answer… cannabis.

Yes, Carol Francey, 70, said she has been smoking weed for five decades and ‘feels as fit as a fiddle’.

In fact, she loves the plant so much, she made the decision to throw away all of her medication, and grow cannabis in her garden instead.

Carol, who openly allowed her son to smoke the drug as a teenager, is an active member of the group Grannies for Green which campaigned for marijuana legalisation in Canada.
Grandmother throws out 'all her pills' and says cannabis is the key
Carol, who openly allowed her son to smoke the drug as a teenager, is an active member of the group Grannies for Green which campaigned for marijuana legalisation in Canada. (Picture: Mercury)
She claims the turning point in her life was when her son Jovian, then 17, was caught smoking weed at school.

She then decided to actively campaign for a change in the law to make cannabis use legal – which will take place in July 2018 – and has enjoyed health benefits as a result.

Carol, from Vancouver, British Columbia, said: ‘I’m not your ordinary granny. I’ll bake cookies in the morning, enjoy a tincture-infused coffee then take my dog Bill for a walk near the river.

‘I cook with and smoke cannabis. Tinctures, vapourizers, dabs, capsules and edible butters all have their place in our house.

‘I grow a grandma-sized garden in a little eight by three foot closet. Growing saves my husband and I thousands of dollars each year.

‘Sometimes on the way home, I’ll stop at a cafe and play scrabble.

‘I’ll then try to squeeze in an hour of accordion practice so I can then play at protests or cannabis festivals. I might do some yoga for sciatica and set up the art studio to paint beside my growing cannabis plants.

‘My grandson, Eli Francey, 7, will be dropped off by his mom a couple of times a week to make cookies, go for walks and play Minecraft. Lately he has been decorating the house for Christmas.

‘He is just seven so it’s too early to explain when he doesn’t see or hear about cannabis and is not part of his home life.

‘He may never show any interest in it as his parents just brew beer. I would not use cannabis with a teen until age 19.

‘My “Coming Out of the Closet Cannabis Club” meets in a coffee shop to welcome newly emerged cannabis users to chat, share resources and support health and social change.’

Carol says she’ll never settle into a stereotypical granny role and believes cannabis has helped her in many aspects of life, including health.

When Jovian was caught smoking the drug, Carol and her husband, Robert Standquist, decided to ‘come out of the closet’ about their own use of cannabis and campaign for its legalisation.

Carol decided to take the extreme step to go against medical advice and threw away her tablets, exchanging them for cannabis-use in different forms.

Carol said: ‘I threw away all my pills [after that]. They had slurred my speech and affected my balance.

‘Now [I have] a little Rick Simpson concentrated oil which relaxes, soothes, repairs and prevents illnesses.

‘A hot coffee with a toasty cannabis tincture works well for arthritis, pain and sleep. [I’ll inhale] a dab for sciatica and I’m after that I can walk. I’m eating healthy foods, walking daily, doing yoga, a little meditation and writing too.’

The married mum-of-one and retired drugs and alcohol counsellor first tried cannabis aged 17 in 1960s Toronto.

Terrified it would damage her reputation as an adviser on drugs and alcohol misuse, Carol kept the habit to herself for decades.

She is now hoping others can be more open about using cannabis and is hopeful for the future after her country decided to legalise it.

‘A hot coffee with a toasty cannabis tincture works well for arthritis, pain and sleep. [I’ll inhale] a dab for sciatica and I’m after that I can walk. I’m eating healthy foods, walking daily, doing yoga, a little meditation and writing too.’

The married mum-of-one and retired drugs and alcohol counsellor first tried cannabis aged 17 in 1960s Toronto.

Terrified it would damage her reputation as an adviser on drugs and alcohol misuse, Carol kept the habit to herself for decades.

She is now hoping others can be more open about using cannabis and is hopeful for the future after her country decided to legalise it.

Carol said: ‘We need to help older people have a better quality of life and give their families the confidence that their care is compassionate and healthy.

‘Cannabis helps you to overcome anxiety about day-to-day life and stop sweating the small stuff.’

Tuesday 19 December 2017

Cerebrospinal Meningitis, here are the facts

Source: Alex Sarkodie MD

Neisseria meningitidis, are bacteria that live harmlessly in the noses and throat of about 15% of the general population.

The carriage rate is even, much higher in adolescents and during epidemics.

Why is Cerebrospinal Meningitis dangerous

Meningococcal meningitis is associated with high fatality (up to 50% if untreated) and severe brain damage awaits 10% of those who survive the disease.

Even when the disease is diagnosed and treated early, 1 out of 8 patients die, often within the first 2 days

Early antibiotic treatment improves survival and reduce complications.

Humans are their only natural hosts. In overcrowded environments, like boarding houses, and during cold dry weather conditions, the bacteria spread very fast, and as they do so, some of the bacteria can transform into disease causing types.

Other risk factors associated with disease-causing bacteria in adolescents, include:

Male gender

Symptoms of upper respiratory tract infection Marijuana use and smoking Close gatherings, including attendance at nightclubs, jamborees.

Disease-causing bacteria invade the bloodstream and multiply rapidly and release their toxins.

In the cranial circulation, they cause meningitis by affecting the brain and the thin brain coverings.

In the small blood vessels, they release toxins that leads to bleeding into the skin. This can lead to extensive destruction of the skin and the surrounding tissues.

SPREAD

N meningitidis is found only in human nasopharynx and is spread via respiratory droplets or contact with secretions.

During the harmattan period, dust winds, cold nights, and having a common cold combine to damage the nasopharyngeal mucosa, allowing the bacteria to enter the blood stream to cause the disease.

The bacteria spread to other persons, via respiratory droplets from colonized individuals, therefore, close contact is required.

There is increased risk, if there was close contact for at least 4 hours during the 7 days before illness onset.

Intimate kissing is a risk factor for meningococcal meningitis in adolescents

Incubation period: Average is 4 days, but ranges from 2-10 days and symptoms, normally, start to show within 4 days

High Risk factors for acquiring meningitis:

1.) Adolescent age group

2.) Living in a group situation

3.) People with impaired immunity

SEROGROUPS:

There are more than 13 serogroups of Neisseria meningitidis, based on the type of polysaccharides in their cell walls. Types A, B, C, Y and W-135 account for 90% of all human infections.

Type B cause sporadic disease in children under 4 years of age.

Outbreak of epidemic diseases are due, mainly to group A and C

In the African meningitis belt, which runs from Senegal to Ethiopia, serogroup A is the usual culprit. During the harmattan season, about 30,000 cases are reported each year.

CLINICAL FEATURES

The disease can affect anyone however, it commonly affects babies, preschool children and adolescents.

The disease is marked by very rapid deterioration in health status, from being well to very sick within hours.

The person may complain of:

Sudden onset of headache

Fever

Nausea and vomiting

Early non-specific signs of meningitis include:

Leg pain, (appears at about 7 hours)

Thirst (at about 8 hours)

Diarrhea (at about 9 hours)

Abnormal skin color (at 10 hours)

Breathing difficulty (at 11 hours)

Cold hands and feet (at 12 hours)

Classic Symptoms:

Purpuric rash, from bleeding into the skin (at 13 hours)

Neck pain or stiffness (at 13 hours)

Photophobia (at 15 hours)

Confusion or Delirium (16 hours)

Seizure (17 hours) Unconsciousness (at 22 hours)

Management

Early recognition of the above signs and symptoms of meningococcemia is an important determinant of survival.

Most children with the invasive meningococcal disease have an illness with symptoms and signs lasting only a few hours to a day.

Many patients are initially thought to have a viral infection. Doctors must beware of the adolescent with fever malaise and purple skin rash

The initial diagnosis can be made by clinical examination and spinal tap that shows purulent spinal fluid.

Treatment

The disease is a medical emergency due to the high fatality rate.

High-dose intravenous penicillin G for 5-7 days is the preferred treatment for infection due to N meningitiis. Ceftriaxone is the alternative.

Prompt treatment of shock with intravenous fluids, heart medications or ventilatory support when needed, may be critical in improving survival.

Prevention and Disease control

Chemoprophylaxis:

Preventive antibiotic medication is given to:

All household contacts

Child care

School contacts or

Anyone exposed to a patient's secretions.

The medications should be given within 24 hours of recognizing the primary case,

Rifampicin, given twice daily for 2 days)

Azithromycin (single dose)

Ciprofloxacin, (single dose)

Ceftriaxone (single dose intramuscularly).

Vaccination

Meningococcal conjugate vaccines confer a protection of more than 5 years

Serogroup B meningococcal vaccine are available. The Polysaccharide vaccines, that are used during outbreaks, offer a 3-year protection for vaccinated individuals.

Who Needs Vaccination

All 11-12year old, should be vaccinated with the meningococcal conjugate vaccine, with a booster dose given at age 16 years old.

All teens may be vaccinated with serogroup B, preferably, at 16 through 18year old.

Adults and younger children with impaired immunity, including sickle cell disease, HIV, spleen problems, may be vaccinated

Recreational cannabis is about to go on sale in California. But it could be hard to find

Gary Robbins

These are anxious days in the mellow world of marijuana.

California is dealing with chaos and comic opera as it prepares to become the latest and largest state to sell recreational cannabis, a cash crop potentially worth billions.

Regulators have only recently chosen which companies will be able to sell the drug when adult-use weed debuts in licensed stores on January 1st, from San Diego to Eureka.

Medical marijuana has been legal in California since 1996. But the sale of recreational cannabis dates only to November 2016, when it was approved by voters.

The path forward is a bit unclear, leaving retailers to look to other cannabis-friendly states for reminders of what to do, and what to avoid.

Lessons abound.
In July, Las Vegas retailers ran out of recreational marijuana days after the state began selling it. Something similar happened in Maryland, with medical cannabis.

The message was obvious: Have plenty of marijuana in the store room. Otherwise, snarky headlines will follow. And the headlines will end up on the DrudgeReport.

On the flip side, California retailers are finding much to admire in Washington and Oregon, where a border rivalry has evolved over who sells the most recreational cannabis.

Companies compete hard, and there’s a lot of “mainstreaming” going on. Retailers get deeply involved in community events, and remind customers that much of the marijuana sales tax goes to schools and health care.

Retailers also are moving to expand their audiences beyond the mix of young and old people typically found in medical marijuana dispensaries.

Oregon has worked especially hard to say that adult-use cannabis is a health and wellness product as much as it is a drug that will scramble your neurons. They’re trying to attract families and health enthusiasts, who are often encouraged to socialize around edible marijuana or topical creams that contain cannabis.

The message resonates in California, where retailers know they need to broaden their markets and clean up their image.

Stores like Urbn Leaf in San Diego’s Bay Park gently reminds older people who might not have seen a joint in a while to call the drug cannabis, not dope or pot.

“We don’t want the image of a typical user to be a 20 year-old guy sitting in his parent’s basement doing bong hits,” said Dallin Young, executive director of the Association of Cannabis Professionals in San Diego.

“We want this to go mainstream.”

A heavy dose of public education is needed, said Lincoln Fish, chief executive of OutCo, a cannabis cultivation company near El Cajon.

“People need to understand the real facts associated with this plant, and realize that they have been given copious amounts of misinformation by anti-drug crusaders who just lump cannabis in with other drugs.

“It doesn’t help, by the way, when publications, including the Union-Tribune, use the word ‘pot’ in every headline.”

The industry has a bigger nemesis — the federal government.

U.S. Attorney General Jeff Sessions has repeatedly reminded retailers that the sale of marijuana is a violation of federal law. It’s unclear whether he’ll lead a crackdown. But the mere threat of one has led banks not to do business with cannabis retailers.

That’s largely turned retail marijuana into a cash business.

It’s also led a lot of communities to tell California marijuana retailers: You’re not welcome here.

More than 70 percent of California’s counties and cities have banned the sale or cultivation of marijuana, or both. San Diego is the only place in San Diego County where marijuana can legally be sold. And only six of San Diego’s nine City Council districts will have licensed stores when recreational cannabis goes on sale on January 1st.

“A lot of people from around the county are going to be very surprised when they learn that,” said Dallin Young of ACP.

Retailers are getting a helping hand from the state, which has effectively thumbed its note at the feds.

In another story that stirred headlines, state Treasurer John Chiang said it might be possible to help retailers by sending armored couriers to their offices to pick up the taxes they owe on marijuana sale.

More recently, California Secretary of State Alex Padilla debuted a website that will make it easier for people who apply for the permits they need to operate in the state’s legal cannabis industry. The website is being publicized by Cheech Marin, a member of the stoner comedy duo Cheech and Chong.

Marin told the Sacramento Bee, “It knocks off a few hours of the community service I had to do.”

Such services could help. But the question remains: How many people will turn out when the sale of recreational cannabis begins?

“It’s tough to forecast,” said Will Senn, founder of Urbn Leaf, which operates two stores in San Diego, and is working on a third.

“We’re preparing for the worst and hoping for the best. Our goal is to keep wait times as low as possible, and to educate people about marijuana.”

Lincoln Fish is more optimistic, saying: “Our consumer research shows that there is a very large contingent of people who want to start using cannabis and have just been waiting because they don't want to get medical cards.”

Medical cards are easy to get, regardless of whether you actually have disease, disorder or disability. But your name is kept on file at a cannabis store if you use it. People worry about how safe their data is.

John Sidline is even more optimistic than Fish.

“Some forecasts peg the California market as getting close to $2 billion in 2018, and as much as $5 billion by 2020,” said Sidline, an executive at the public relations firm the Cannabis Story Lab in Portland, Oregon.

“Because the industry is building on top of an existing 20 year medical marketplace, the ramp to address adult-use recreational (cannabis) won’t be long, and there is already pent-up demand for the product.”

United States: Canadian Reporting Issuers With U.S.-Related Cannabis Activities

by Michael Lipton, QC and Chantal A. Cipriano, Dickinson Wright PLLC
 
The House of Commons has passed the third reading related to the Cannabis Act (the "Act"). Scheduled to come into force no later than July 2018 (subject to Parliamentary approval and Royal Assent), the new law will permit the recreational use of cannabis and sets out the provisions to regulate its possession, production, distribution, and sale. The Act is in addition to the existing Access to Cannabis for Medical Purposes Regulations under the Controlled Drugs and Substances Act, which, subject to some coordinating amendments with the Act, will remain in force.

The push by the federal government to have its cannabis legislation in place by July 2018 has left provincial governments and industry regulators scrambling to draft their own legislation and guidelines. In the haste to legislate cannabis in Canada, a glaring concern remains for industry participants and investors: cannabis continues to be a prohibited substance under U.S. federal law but is permitted under certain state laws that have legalized cannabis-related activities.

This, in turn, has left Canadian reporting issuers with U.S.- related cannabis activities uncertain of their treatment by the Canadian Securities Administrators ("CSA") and the Toronto Stock Exchange ("TSX"). To complicate matters further, the Department of Justice issued guidance in 2013 that it would not generally enforce the federal prohibitions of any U.S. state that has authorized marijuana activity through enforcement of their own narcotics laws so long as such states have implemented a strong and effective regulatory framework. However, the federal guidance is subject to change, rescission, or alteration at any time. In the event the U.S. federal prohibition is enforced, there could be material consequences for an issuer with U.S. marijuana-related activities, including prosecution and asset seizure.

CSA

In CSA Staff Notice 51-352, Issuers with U.S. Marijuana- Related Activities, the CSA has acknowledged that while most jurisdictions have a uniform national framework for marijuana regulation, there remains a conflict between U.S. state and federal law.

Securities regimes across Canada are primarily disclosure-based. Disclosure must be timely and accurate to ensure that material facts and risks are presented fairly in order for investors to make informed investment decisions. The CSA takes a disclosurebased approach premised on the assumption that marijuanarelated activities are conducted in compliance with the current laws and regulations of a U.S. state where such activities are legal. The Staff Notice outlines the specific disclosure necessary to fairly present all material facts, risks, and uncertainties and imposes disclosure requirements according to the following categories: (i) all issuers with U.S. marijuana-related activities; (ii) U.S. marijuana issuers1 with direct involvement in cultivation or distribution;2 (iii) U.S. marijuana issuers with indirect involvement in cultivation or distribution;3 and (iv) U.S. marijuana issuers with material ancillary involvement.4 The CSA expects that disclosures and any risks be evaluated and monitored on an ongoing basis and amended and communicated as necessary immediately to investors in public filings. U.S. marijuana issuers who do not provide appropriate disclosure may be subject to receipt refusal in the context of prospectus offerings, requests for restatements of noncompliant filings, and referrals for appropriate enforcement action.

The CSA has stated that if an exchange lists a U.S. marijuana issuer that discloses the risks in accordance with the Staff Notice, the listing does not change the treatment of the issuer's marijuana-related activities under U.S. federal law.

TSX

The TSX is aware that a number of U.S. states have legalized the cultivation, distribution, or possession of marijuana to varying degrees and subject to various conditions. However, the TSX has noted that marijuana remains a Schedule I drug under the U.S. federal Controlled Substances Act, which means it is illegal under U.S. federal law to cultivate, distribute, or possess marijuana in the U.S. Moreover, financial transactions involving proceeds generated by or intended to promote marijuanarelated business activities in the U.S. could form the subject for a prosecution under U.S. federal money laundering legislation. Issuers with ongoing business activities that violate U.S. federal law are not complying with the TSX Company Manual as indicated in Staff Notice 2017-00009.

Business activities may include (i) direct or indirect ownership or investment in entities engaged in activities related to the cultivation, distribution, or possession of marijuana in the U.S.; (ii) commercial interests or arrangements with entities engaged in activities related to the cultivation, distribution, or possession of marijuana in the U.S. that are similar to ownership of or investment in such entities; (iii) providing services or products that are designed for or targeted at entities engaged in activities related to the cultivation, distribution, or possession of marijuana in the U.S.; or (iv) commercial interests or arrangements with entities engaging in the business activities described in (iii). The business activities in (iii) and (iv) are referred to as Ancillary Services Activities.

In the context of the TSX's continued listing review of listed issuers in the marijuana sector, TSX expects to group issuers into two categories:
  1. Category 1 is composed of issuers with business activities that involve the cultivation, distribution, or possession of marijuana in any jurisdiction.
  2. Category 2 is composed of issuers that do not cultivate, distribute, or possess marijuana but appear to be engaging in Ancillary Services Activities.
TSX has determined that issuers operating in violation of U.S. federal law are not acting in compliance with TSX listing requirements. Accordingly, TSX may exercise its discretion to initiate a delisting of issuers engaged in such activities under Part VII of the TSX Company Manual.

Gaming and Cannabis

The Nevada Gaming Commission has taken the position that as long as marijuana is illegal under U.S. federal law, gaming licensees must not have any involvement with or participate in the marijuana industry – doing so would violate the requirement for licensees to obey all laws, including federal laws.

The proposed cannabis legislation in Canada contemplates each province regulating marijuana-related activities. Under the proposed Cannabis Act, the federal government would generally be responsible for setting conditions and licensing the cultivation and manufacture of cannabis and its related products, while provinces and territories will generally be responsible for regulating their distribution and retail sale. In Ontario, the regulator will be the Alcohol and Gaming Commission of Ontario ("AGCO").

In our assessment, and unlike the position in Nevada, we believe AGCO will not object to any gaming registrant or qualifier participating in a legal marijuana program stipulated by federal legislation if enacted in July 2018. However, in a jocular vein, we very much doubt that AGCO will be renamed as "Alcohol, Gaming, and Marijuana Commission of Ontario."

Monday 18 December 2017

CBD is a non-psychoactive compound in marijuana that shows promise in epilepsy and pain therapy, so the DEA wants to class it with heroin

 
 
The World Health Organization's new report on cannabidiol (CBD) found that the compound (which does not produce any kind of high -- and may actually counteract the psychoactive properties of THC) is not addictive, has no potential for abuse, and shows promise in a number of medical trials.

So of course Trump's Drug Enforcement Agency wants to class it as a Schedule I narcotic, reserved for substances with "a high potential for abuse"; "no currently accepted medical treatment use in the U.S."; and "a lack of accepted safety for use of the drug or substance under medical supervision."

CBD is currently in US Phase III clinical trials as an effective treatment for epilepsy, and in earlier trials for other applications.

Apologists for Trump's prohibition on using the phrases "evidence-based" and "science-based" say that these phrases are used ""as a bullying tactic, in lieu of an actual argument" and argue that the phrase "CDC bases its recommendations on science in consideration with community standards and wishes" isn't a denial of objective reality, because "Science is (ought to be) value-free, yet CDC and more broadly federal policy should embody values too."

But the plan to schedule CBD is a crisp, unambiguous example of how policy making in the absence of evidence, because of values that are unsupported by evidence, produces terrible outcomes.

People with chronic pain have turned to extremely dangerous substances to treat them, prompting an epidemic that has killed more Americans that the Vietnam war. The evidence for the existence of a non-habituating, safe pain treatment is a major cause for celebration.

But the Trump administration and the Republican party represent a base whose "values" are largely aligned in opposition to the legalization of any part or derivative of marijuana. So the "evidence" of the harm from marijuana is weighed against the faith of the policymakers and their base, and the evidence is discarded in favor of the "values," to the detriment of individuals who are doomed be denied an effective treatment for debilitating illness, and to society because of the loss of those peoples' productivity, the pain and suffering of their families, and the foreclosure of CBD to help mitigate the opiod crisis.
Instead, CBD is thought to have a broad range of actions on the endocannabinoid system—a collection of neurotransmitters that bind to receptors in the nervous system to mediate a variety of physiological processes, including mood, appetite, pain, and inflammation. Though researchers are still working out all of CBD’s functions, studies on animals and a small number on humans have found no evidence that it is toxic or addictive. It’s a relatively safe compound that is no more addictive than placebo in studies.
In terms of therapeutic potential, several clinical studies have found that pure CBD is effective at treating some types of epilepsy. In some cases it can completely eliminate seizures. There’s even a pure CBD product (Epidiolex®) currently in phase III trials.
And researchers are also looking into using CBD for a range of other medical conditions.
Though this work isn’t as far along as the epilepsy research, the ECDD noted that there’s positive preliminary data for treating a range of conditions. These include Alzheimer’s disease, Parkinson’s, anxiety, pain, nausea, inflammatory bowel disease, and rheumatoid arthritis. There’s also evidence to suggest that CBD may be helpful in combating opioid addiction.
With the expanding data and the growing acceptance of marijuana in the States, there has been a crescendo of interest in CBD and other cannabis products. Yet, the DEA has doubled-down on its position that CBD, as a part of marijuana, is a schedule I drug.
In December of last year, the DEA made the point clear by creating a new drug code for marijuana extracts, including pure CBD.

Non-citizens can be deported for pot use


Federal visas override state marijuana law


Legal residents in the United States need to be aware that they can still face deportation if they possess, grow, sell or consume marijuana, even in states such as Colorado where it is legal to do so.
Those laws, however, only protect citizens of the states that have legalized medical or retail marijuana.
Because of a recent increase in the number of legal residents who were deported after being convicted of a marijuana crime, two groups — Servicios de la Raza and the Marijuana Industry Group — have joined forces to instruct legal residents of the pits and perils of not following the law.
Together, they have produced an instructional video to help explain to non-citizens — including those married to citizens for less than two years — that while certain states have legalized pot use, it's still a federal crime.
And because their visas come from the federal government, they can be deported if caught possessing or using marijuana.
"We work on the ground, in the community and have seen firsthand the positive effects of marijuana tax dollars on community programs, and marijuana creating job opportunities and helping people get off of opioids," said Rudy Gonzales, la Raza executive director.
"When we started hearing about legal-permanent residents and other immigrants being deported for using marijuana, or for having images of marijuana on social media or cellphones, we ... realized that most people living in Colorado or other states where marijuana is legal do not know the difference between state and federal laws."
Gonzales said federal law enforcement agents have started a new tactic of checking the cell- phones and social media posts of non-citizens for evidence of marijuana use.
Last year, Immigration and Customs Enforcement deported more than 240,000 undocumented immigrants. Not all of these are related to cannabis use, but possession, confession or use of even small amounts of pot can result in detainment or deportation.
"The legal and licensed businesses in the cannabis industry are part of the communities in which they operate," Kristi Kelly, executive director of the group said. "To the extent there is a gap in that education, particularly one of such significant human consequence, we have a responsibility to address it. We wanted to educate them about the laws and minimize accidental deportation."

Will people forsake booze for legal weed?

Antonella Artuso

Will a culture so tied to alcohol switch allegiance once recreational cannabis is readily and legally available?

A recent study out of the University of Connecticut looked at alcohol sales in jurisdictions with medical marijuana, and found the two substances to be substitutes, with monthly booze sales falling 13%.

A 2016 Deloitte study predicted some alcohol consumers will migrate to legal recreational marijuana.

Dan Malleck, associate professor in Health Sciences at Brock University, said the U.S. study looked at medical marijuana, and the findings suggest that people are switching if they’re using alcohol to self-medicate for conditions like stress.

However, societies have been developing symbols around alcohol consumption for thousands of years, he said.

”So raising a glass or buying rounds, or things like that, are just not something that has a parallel within cannabis consumption,” Malleck said. “Cannabis is about sharing the joint or sitting around in a room smoking and talking. It’s got it’s own culture with it and, I think, that is partly because of the way it’s consumed and partly because of the I guess surreptitiousness around how it had to be consumed under prohibition.

“But I don’t think that we will see it replacing like ‘raising a glass.’”

The Ontario government is certainly not concerned about any impact on alcohol sales.

Asked if his ministry has evaluated any potential changes to alcohol revenues in a legal pot world, a spokesperson for Finance Minister Charles Sousa replied succinctly – “no.”

Of course, the fact that the Ontario government has full control of both alcohol and cannabis sales in the province ensures it wins whichever way the consumer bends.

The 2017 Ontario budget projects “stronger overall performance” from the LCBO, even without its expansion into selling recreational marijuana.

Marijuana use is usually viewed from a public health point of view as less dangerous than alcohol, Malleck said.

It doesn’t tend to lead to binging or other negative behaviours associated with alcohol use, he said.

“People who smoke weed in general tend to be less violent, less rowdy, sitting around giggling,” he said.

Under the legalization framework, though, recreational pot cannot be consumed in public places like bars.

Also, from a law and order perspective, the technology to detect drug impaired driving is not as sophisticated as that aimed at drunk drivers, he said.

Malleck said he would have supported selling recreational marijuana at regular LCBO stores but some citizens and “histrionic” public health types objected.

“It’s like a legitimate high versus what some people still see as an illegitimate high in cannabis,” Malleck said.

Friday 15 December 2017

The World Health Organization Says That Medicinal Cannabis Has No Abuse Potential

Kasandra Brabaw

Despite concerns from some that marijuana — even medical marijuana — could be a "gateway" to harder drugs, it seems that health experts aren't too worried.
In fact, the World Health Organization (WHO) released a report Wednesday specifically stating that cannabidiol (also known as CBD), a component in medical marijuana, does not have a risk for abuse.
"Current evidence shows that cannabidiol is not likely to be abused or create dependence as for other cannabinoids (such as Tetra Hydro Cannabinol (THC), for instance)," the report states.
The WHO was looking into CBD due to "increased interest" in using marijuana in medical care, and especially palliative care, or care for people who have life-threatening illnesses, BuzzFeed reports.
"In general, clinical studies have reported that even high doses of oral CBD do not cause those effects [addiction or potential for abuse] that are characteristic for THC and for cannabis rich in THC," said the report. CBD had also been found to have "relatively low toxicity."

The majority of the effects of marijuana can be nailed down to two compounds: CBD and THC (tetrahydrocannabinol). THC is responsible for the psychoactive effects that make you feel high.
CBD, on it's own, doesn't cause those same effects. Since this report speaks only about the potential for abuse and dependance of CBD, this doesn't mean that there's no possibility of ever getting addicted to marijuana, and other experts have actually spoken about addiction as a possible effect.
"It’s very difficult to pin down the probability of addiction, because so many things determine it, but...somewhere around nine to 10% of regular users of marijuana will become dependent," David Casarett, MD, author of Stoned: A Doctor's Case For Medical Marijuana, told Refinery29 in 2015. 
"That's compared to between 13 and 15% of [regular users] becoming dependent on other drugs, like cocaine."
For now, the WHO suggests that CBD could be useful in treating medical conditions and recommends that it not be regulated by the government.

You want ganja to be legal in India? These MPs want it too

The MPs call the criminalisation of cannabis consumption 'elitist' as it has been the intoxicant of the poor.

TNM Staff 

There are many issues our lawmakers need to discuss in the Winter Session of Parliament, which commenced on Friday. These include the Goods and Service Tax, the Consumer Protection Bill, the National Sports University Bill, The Prevention of Corruption (Amendment) Bill … and reportedly, a private member’s bill to legalise marijuana.

You read that right.

Dharamvir Gandhi, a Member of Parliament from Patiala, is seeking to legalise marijuana possession and consumption in India among other “non-synthetic” intoxicants.
   
Currently, the Narcotics Drugs and Psychotropic Substances (NDPS) Act of 1985 criminalises possession, trade, transport and consumption of cannabis, among other narcotic and psychotropic substances.

A cardiologist by profession, Dharamvir was associated with the Aam Aadmi Party until he was suspended in 2015 along with another MP, Harinder Singh Khalsa, from primary membership for “anti-party activities”.

He moved a private member’s bill to legalise the recreational use of marijuana last year as well, and even earned the support of the late actor and politician Vinod Khanna, a BJP MP at the time, and Biju Janata Dal (BJD) MP from Odisha, Tathagata Satpathy.

Tathagata is well known for his open support for the cause of legalising marijuana. In a 2014 Reddit AMA (Ask Me Anything) thread, he declared that he had smoked cannabis many times as a college student. “In villages of Orissa, many people openly smoke and, as their representative, I am not entitled to be judgmental,” he had said.

The MP, who is the also the owner and editor of leading Odia daily Dharitri and English daily Orissa Post, is known to voice his views on issues quite unabashedly. Just last year, he even sported a kurta made of hemp fabric to the Lok Sabha.

Both Dharamvir and Tathagata have justified the legalisation of recreational marijuana multiple times in the last couple of years.

Ban on marijuana elitist?
Tathagata has called the criminalisation of cannabis possession and consumption ‘elitist’. In an interview to Deeptiman Tiwary for the TOI, Tathagata said that intoxication has been part of societies globally and mentions of the same can be found in old texts also.

“In Odisha [where cannabis consumption is not illegal], people smoking chillum is a common sight.

It is not something you make note of, just as you don't notice someone drinking water or having tea,” he had observed. He added that the problem arises only when an intoxicant is allowed to overpower one’s life; then one should try to get out of it.

Keeping pace with current times
Dharamvir had told Hindustan Times last year that the NDPS Act came into being to meet the UN Conventions on Drug Policy. Tathagata had also mentioned this in his TOI interview. The NDPS Act was also a response to the US placing a ban on cannabis and other drugs.

Calling India the ‘wannabe’ America of the ‘50’s and ‘60’s, Tathagata said that cannabis suffered its fate because it was the intoxicant of the poor, and was not seen with the same eye as a wine glass held in the hands of the rich.

About half the states in the US, and at least 16 countries around the world, have since legalised marijuana use, especially for medicinal purposes like “treating chronic pain, nausea after chemotherapy, epilepsy and symptoms of multiple sclerosis”, reported Manu Balachandran for Quartz India.

The changes the private member’s bill proposes in the NDPS Act, therefore, are to separate the clubbing together of ‘soft’ intoxicants with artificial ‘hard’ drugs like cocaine, heroin and smack.

This de-linking has also found support from Romesh Bhattacharji, former Commissioner of the Central Bureau of Narcotics. He had told Debayan Roy from News18 that the NDPS Act been victimising people since 1985 – the year it came into effect.

He quoted data from Punjab between 2001 and 2011, and said that of the 25,003 people behind bars under the NDPS Act, only 10 to 60 people were drug traffickers. The others were merely poor people found possessing soft drugs.

Creation of a drug mafia, harder intoxicants
Dharamvir has argued that the ban and subsequent ‘war on drugs’ resulted in the creation of a drug mafia that supplied more dangerous and potent drugs, like cocaine, that are much more addictive.

Due to the hefty profits to be made in the underground drug trade, it has led to rivalries, which then led to gang wars. It has also pushed aggressive marketing, which has led more people to hard drugs.

“Consequently, the petty traditional drug users are turning to the easily available and aggressively marketed, addictive and dangerous street drugs,” Dharamvir told HT. He hoped that the NDPS Act would be amended so that “cheap, regulated and medically supervised supply of traditional and natural intoxicants like ‘afeem’ and ‘bhukki’ (opium)” can be made available. This move, according to him, will push a fewer people towards more dangerous and harmful intoxicants.

Tathagata pointed out in 2015 that the ban on sale and possession of natural and soft drugs, like bhang and cannabis, led people to turn to alcohol. Alcohol has a higher incidence of addiction compared to cannabis – 16% and 9% respectively.

Olga Khan wrote for The Atlantic that the chances of getting addicted to cannabis if you smoke it after you’re 25 years old are “essentially nil” and the withdrawal experienced by those who give up smoking marijuana are also much fewer. The piece, however, warns that most of these studies were conducted during the age of prohibition, when people were not able to get their hands on weed easily, hence skewing statistics.

Time for change?
The most recent person to join the debate for the legalisation of marijuana is Women and Child Development Minister Maneka Gandhi. In July this year, she called for the legalisation of marijuana for medicinal purposes. She made the suggestion at a meeting, which scrutinized the National Drug Demand Reduction Policy draft.

Citing the US, she said that legalisation of cannabis for medicinal usage had ultimately resulted in lesser instance of drug abuse. She further told PTI that marijuana should be legalised especially if it helps in treating cancer.

Norway Has Decriminalized Drug Use

Jon Hiltz

A significant win for drug reform was announced on Sunday with news that Norway’s Parliament has effectively decriminalized all drug use.

The Scandinavian nation stated that the responsibility of handling the estimated 10,000 drug addicts or more, most of whom are addicted to heroin, will transfer from the country’s justice system to its health department.

The move received overwhelming bipartisan support from the Labor, Conservative, Socialist and Liberal parties of Norway.

“[We] will stop punishing people who struggle, but instead give them help and treatment,” said Nicolas Wilkinson, the health spokesman for the Socialist Left Party. Wilkinson added that this move is the beginning of major reform for the country where the government will “switch the system from punishment to help.”

The deputy chairman of Norway’s Parliamentary Health Committee, Sveinung Stensland, also stated “it is important to emphasize that we do not legalize cannabis and other drugs, but we decriminalize.”

Although drug crimes such as trafficking and manufacturing still exist, the move has been hailed as a way to free up precious police resources.

In February, the Health Committee will head to Portugal to research best practices for implementation. Portugal decriminalized all drug use in 2001 and has seen incredible success.

What You Need to Know About Marijuana & Your Sexual & Reproductive Health

By Kristen Fischer

Here's how marijuana use could affect your sexual & reproductive health

Now that marijuana has been legalized in several states, Americans are smoking weed more than ever. Naturally, this could have an impact — both positive and negative — on various aspects of their lives, including sex and fertility. To get a better idea of this relationship, Stanford recently conducted a survey in which participants were asked how many times they’ve had intercourse with a member of the opposite sex in the past four weeks and how frequently they smoked marijuana over the past year.

It turns out, those who use pot are having about 20 percent more sex than those who don’t, the findings indicated. Of those studied, 24.5 percent of men and 14.5 percent of women said they had used marijuana. Women who didn’t have marijuana in the past year had sex about six times during the previous four weeks — that number went up to 7.1 for daily pot users. Among men, the corresponding figure was 5.6 for nonusers and 6.9 for daily users.
While the study’s data may seem to point to a direct correlation between sex and marijuana, the reality of the relationship is not as easily explained.
Below are facts you’ll want to know about marijuana use and your sexual and reproductive health.

How many people use marijuana?

The National Institute on Drug Abuse reports that more than 20 million adult Americans are current marijuana users. The drug is legal for medical or recreational use in 29 states — a number that could climb.

Can using marijuana lead to more sex?

Marijuana is linked to having more sex, but before you smoke up, keep in mind that the research doesn’t say that consuming more marijuana equals having more sex. A study by Stanford University School of Medicine found a positive correlation between sexual intercourse frequency and marijuana.

While the correlation is strong, it is not causal.

“Marijuana use is very common, but its large-scale use and association with sexual frequency hasn’t been studied much in a scientific way,” Dr. Michael Eisenberg, an assistant professor of urology and senior author said in a statement.

Can using marijuana lead to better sex?

Unfortunately, marijuana doesn’t seem to impact sexual performance. The medical community has largely indicated that frequent marijuana use may actually impair sexual desire or performance.

Nonetheless, the Stanford analysis of more than 50,000 Americans ages 25 to 45 found that using the illegal drug doesn’t seem to impact sexual performance. The findings were published in the Journal of Sexual Medicine.

“Frequent marijuana use doesn’t seem to impair sexual motivation or performance. If anything, it’s associated with increased coital frequency,” Eisenberg said.

Can heavy marijuana use impact chances of conceiving?

If you and your partner are trying to have a baby, marijuana might be making it more difficult.

According to a study by the Oxford University Press, prolonged marijuana use may lower a male’s sperm count by nearly a third.

“The men who smoked marijuana more than once a week produced sperm counts that were 28 percent lower, on average, than those who smoked marijuana less frequently or not at all,” according to SexInfo Online.
Heavy using has also been linked to erectile dysfunction, but other studies say it stimulates activity in brain regions involved in sexual arousal and activity.

So enjoy yourself, but know when marijuana could enhance — or hurt — your sex life.

Thursday 14 December 2017

Leave us alone to choose our medicine

By Kamloops This Week
 
It is our fundamental right to choose our prescription medication of recreation, be it beer or tobacco.

How ironic this article was printed in KTW on Dec. 5, the end of prohibition in the United States.

That day was also the birthday of my best friend, who drank herself to death.

By my count, there are 10 stores in Kamloops that sell marijuana and I have personally welcomed each and every one as they are needed.

They are needed, unlike the stores that sell alcohol, which are on every corner of this town and now in food stores.

We all know the statistics on alcohol, tobacco and pharmaceutical consumption when abused. No one has ever died from using marijuana.

I have a prescription licence for pot from Dr. Ian Mitchell. It cures what ails you.

Dispensaries are the best place to buy and get information. They are relaxing, non-judgmental and clean environments.

Let’s get our facts straight about marijuana. Go online to leafy.com for more information.

The City of Kamloops is holding a public hearing on the future of pot dispensaries. It will be held on Tuesday, Dec. 19, at 7 p.m. at Sandman Centre.

I look forward to seeing people there supporting the right to choose.
 

Here’s What Jeff Sessions Discussed In Secret With Anti-Marijuana Activists

By Tom Angell

Last week, U.S. Attorney General Jeff Sessions held a behind-closed-doors meeting about marijuana with anti-legalization activists.

Now, thanks to the fact that Sessions inadvertently showed an agenda for the meeting to a TV camera that was in the room to capture introductions — along with some high-tech sleuthing — we know what the prohibitionists discussed in secret after reporters were kicked out.

A Twitter user with the handle @MentalMocean was able to enhance a screen capture of the document that Marijuana Moment posted.

Enhanced photo.
The document appears to read:
Agenda
Bertha Madras: Marijuana is not a substitute for opiates as a pain medication.
Dr. Hoover Adger: The harm from today’s marijuana.
Dr. Bob DuPont: The effect of marijuana on drugged driving.
David Evans: The role that the Food and Drug Administration can and should [obscured]
[obscured] The organizations you can speak for and what you and they are [obscured] people from recreational marijuana use.

[obscured] law enforcement thinks of the commercialization of [obscured] law enforcement would support an enforcement initiative.

[obscured] course of marijuana commercialization in the states if the [obscured] not intervene.

The enhanced photo makes clear that the anti-legalization activists made a concerted pitch during meeting to convince Sessions to launch a federal crackdown on states that have ended cannabis prohibition.

In attendance, according to video of the opening introductions captured by a pool photographer and posted by C-SPAN, were:
  • Edwin Meese III, U.S. attorney general under the Reagan administration
  • Kevin Sabet, president and CEO of Smart Approaches to Marijuana
  • Bertha Madras, a former Office of National Drug Control Policy staffer and a member of President Trump’s Commission on Combating Drug Addiction and the Opioid Crisis
  • Robert DuPont, former director of the National Institute on Drug Abuse
  • David Evans, executive director of the Drug Free Schools Coalition
  • Dr. Hoover Adger, Johns Hopkins Hospital
“I think it’s a big issue for America, for the country, and I’m of the general view that this is not a healthy substance,” Sessions said at the beginning of the gathering. “I think that’s pretty clear.

And then have the policy response that we and the federal government needs to be prepared to take and do so appropriately and with good sense.”


“I appreciate the opportunity to hear your analysis on marijuana and some of the related issues,” Sessions told the group. “I do believe, and I’m afraid, that the public is not properly educated on some of the issues related to marijuana. And that would be a matter that we could, all of us together, maybe be helpful in working on and that would allow better policy to actually be enacted.”

The group’s roundtable discussion itself, which took place after initial introductions, was closed to the press.

The gathering comes as the Justice Department’s overall position on marijuana policy remains uncertain. Sessions has in recent weeks sent mixed signals about his plans for federal marijuana enforcement under the Trump administration.

Last month, he testified before Congress that an Obama-era Justice Department memo that generally allows states to implement their own marijuana laws without interference remains in effect. But he separately told reporters at a briefing that his department is actively conducting talks about potential changes to the policy.

British man faces prison in Dubai for smoking cannabis in the UK

"They are saying I smoked it here - but I did [it] back home."


A British man faces two years of jail in Dubai after he was arrested for smoking marijuana before he arrived in the UAE.

Connor Clements, 24, traveled from Liverpool to Dubai earlier this year when he got a job as a waiter in the Emirate. However, when he took a routine drug test required for this employment contract, he tested positive for cannabis, according to British media.

Dubai authorities moved quickly to arrest him and put him in prison. Clements has been released on bail, but he claims he was sleeping on a prison cell floor with 25 other detainees while he spent a few weeks in jail.

“I was in a rut. My sister lives here and I had an opportunity to change my life and it's been nothing but a living nightmare," Clements told the Liverpool Echo, emphasizing he had not committed a crime in the UAE.
"They are saying I smoked it here - but I did [it] back home, they have got no proof... I used to smoke a lot back home. I came here to stop everything," he said.
"I was coming over here to totally change my life around. I had a new job and met loads of nice people."
Connor Clements
Connor Clements in the UAE Source: dailymail
During a very brief court appearance, Clements was handed down a two-year sentence. He claims he wasn't given adequate time to explain his situation and that the court appearance lasted less than one minute.

Now, out on bail, Clements is awaiting an appeal hearing. His passport has also been confiscated.
The UK's Foreign Office said it is assisting Clements with the case.
 "Our staff in the UAE are assisting a British man following his detention in Dubai. We have visited him on several occasions, made calls to the prosecutor's office to get updates on his case, and are in regular contact with his family," a spokesperson said, according to The Independent.
Clements' appeal will take place a few days before Christmas on Dec. 25, according to media reports. He reached out to British media in hopes of raising awareness about his case.
"I don't want to go back in prison," he said.
Connor Clements
Connor Clements with a dog Source: cetusnews
The UAE has a zero tolerance policy when it comes to drugs, according to the British Foreign and Commonwealth Office.
However, while the UK may be seen as more lenient when it comes to marijuana use, possession can technically still land someone in prison for up to five years. Unlimited fines can also be placed on individuals caught with cannabis.

Wednesday 13 December 2017

Sessions and Christie Must Stop Telling Lies About Marijuana

By

Congress just gave the Rohrabacher-Blumenauer amendment, which bars the Department of Justice from using federal funds to prosecute people buying or selling medical marijuana in states that have legalized it, a temporary reprieve until Dec. 22.

However, as Rep. Earl Blumenauer, (D-Ore.) stated, “Two weeks is not enough certainty," especially when you are talking about patients’ well-being and a North American cannabis marketplace largely made up of small business owners and their employees that is expected to grow 33 percent to nearly $10 billion in 2017 and create tens of thousands of new jobs in the New Year.

A recent Gallup poll revealed support for legalizing marijuana is the highest it’s been since the question was first asked in the US in 1969. The poll showed a four-point uptick from a year ago with 64 percent of Americans supporting legalizing marijuana for medical and adult use.

In addition to Democrats or independents supporting legalization, Republicans for the first time backed fully legalizing cannabis, a plant found to be far less harmful than alcohol and tobacco, two federally legal substances under US law.

However, despite widespread bipartisan support for legalization and the positive impacts cannabis has had on patients, US Attorney General Jeff Sessions seems set on launching another failed federal “War on Drugs” campaign and cracking down on states that have partly or completely legalized marijuana use.


Sessions’s misguided approaches are mirrored by an equally disturbing misinformation effort by the chairman of the Trump Administration’s Commission on Combating Drug Addiction and the Opioid Crisis, the unpopular New Jersey Governor Chris Christie.

In the fall, Christie released a letter announcing recommendations made by the opioids commission and at an event announcing these recommendations, he called supporters of marijuana legalization "crazy liberals" who want to "poison our kids." Christie went on to compare medical marijuana laws to the over-prescribing of opioids that led to the current opioids epidemi c.

Many Americans and healthcare professionals were equally shocked and angered by the Commission’s report and Christie’s remarks. In fact, Dr. Chinazo Cunningham, a professor of medicine at the Albert Einstein College of Medicine that conducted the First Long-Term Study on Medical Marijuana's Impact on Opioid Use for Pain, stated to CNN:
I was surprised to see negative language about marijuana in the opioid report. Research that examines pain and marijuana shows that marijuana use significantly reduces pain. In addition, the majority of studies examining marijuana and opioids show that marijuana use is associated with less opioid use and less opioid-related deaths.

On the other hand, the opioid epidemic, which was largely sparked by a quadrupling of federally legal doctor-prescribed painkillers, such as Oxycontin and Vicodin since 1999, caused 59,000 deaths due to overdoses in 2016 according to a recent investigation by the New York Times. Tragically, this makes deaths from opioids the leading cause of death of Americans under age 50.

Unfortunately, having lost loved ones to the nation’s opioid crisis, I think everyone agrees we must do everything we can to address our failed drug policies.

However, we shouldn’t tolerate lies about cannabis and successful approaches to fairly license, tax, regulate and enforce the plant. We also shouldn’t accept Christie’s and Sessions’s failed “War on Drugs” rhetoric, which only appears to be filled with personal ideologies and void of any sound supporting data and scientific facts as a viable drug reforms for our country. We can and must do better.

The truth is, science years ago discredited the idea that cannabis is a gateway drug  and scientific research increasingly shows that access to medical marijuana can help decrease rates of opioid addiction and death.

The 2015 National Bureau of Economic Research ’s analysis found states with medical cannabis laws saw as much as a 35 percent drop in substance abuse treatment admissions and a 31 percent reduction in opioid overdoses.

A report issued earlier this year by Drug and Alcohol Dependence also found that states with legalized medical cannabis programs saw an average drop in opioid use of 23 percent in states after legalizing medical cannabis.

In this era of “alternative facts” and misinformation, it is critical that Americans hold elected and appointed officials like Christie and Sessions accountable for making statements masked as facts.

If our nation is serious about recognizing the factors that lead to its opioids crisis and failed ‘War on Drugs’ policies, we can no longer tolerate Reefer Madness scare tactics as a viable policy approaches.

Rather, we should come together to call on Congress to act and to put an end to this cycle of uncertainty and permanently protect state medical marijuana programs — and adult use — from federal interference.

Medical marijuana surges in popularity in the Netherlands




Cannabis
. Cannabis / Wikipedia
The demand for medical marijuana is soaring in the Netherlands. Over the past five years the number of doctor's prescriptions for medical marijuana grew by more than 400 percent to over 50 thousand this year, according to figures from the foundation of pharmaceutical statistics SFK, AD reports.

The number of prescriptions for cannabis oil picked up from pharmacies grew by a massive 60 percent this year. According to SFK, this form of medical marijuana is growing in popularity because it is easier for patients to use than, for example, 'floss' - dried flower heads from which you make tea.

The use of medical marijuana, which is only available with a doctor's prescription, took off in the Netherlands in 2016 with an increase of 75 percent. Jan Dirk Kroon of the SFK estimates that around 8 thousand people in the Netherlands use medical marijuana. "But that is a conservative estimation", he said to the newspaper.

Doctors have mixed feelings about medical marijuana as it is not an official medicine, but patients increasingly ask for it, the Dutch association for general practitioners NHG said to AD.

The association is therefore working on a 'position' on medical marijuana, which will be published next year. "We advice GPs to prescribe medical cannabis if the patient with chronic complaints asks for it and if conventional treatment does not help or cause too many side effects." Monique Verduijn of the NHG said to the newspaper.