Recent interest in cannabis is now leading to growing evid ence that it may help treat several cancer-related symptoms.
(STF/AFP/Getty Images)
THE QUESTION
My father is 84 and has been diagnosed with terminal cancer. The medication
he has been prescribed for pain isn’t working. He wants to try medical
marijuana. But getting a doctor to prescribe cannabis is like pulling teeth. His
doctor says there isn’t enough scientific evidence to support its use, even
though it’s legally permitted by the Canadian government. What can I do to get
my father cannabis?
THE ANSWER
I’m surprised the doctor didn’t comply with your father’s wishes.
One of the main goals of medicine is to relieve suffering, explains Dr. David
Juurlink, a
drug-safety expert and head of clinical pharmacology and toxicology at Sunnybrook Health Sciences Centre.
When the regularly prescribed drugs don’t provide adequate pain relief,
doctors should be willing to consider a patient’s request for medical cannabis,
Juurlink
says.
Of course, your father’s doctor may have raised a valid point that far more
studies have been done on conventional prescription drugs than on the medical
uses of marijuana.
However, recent interest in cannabis is now leading to a growing body of
research that suggests it may help treat several cancer-related symptoms. Not
only does it appear to ease
pain in some patients, but cannabis might also alleviate the loss of
appetite and nausea caused by chemotherapy cancer treatments.
Dr. Vincent Maida, a
consultant in palliative medicine and wound management at the William Osler Health Centre in Toronto, has been looking
after dying patients for more than two decades and considers himself to be an
“early adopter” of medical cannabis. He began conducting research studies on cannabis in the
mid-1990s after some of his patients reported feeling better when they used
recreational marijuana.
Maida, who
is also an associate professor at the University of Toronto, explains: “No one
has ever died directly of a marijuana overdose. Yet many people die every year
from opioids,” which are the main compounds used in many prescription pain
relievers.
Juurlink
echoes his sentiments. “From a safety perspective, medical cannabis is miles
ahead of many of the other drugs that sit on our pharmacy shelves.”
He says there is a small risk that some patients may suffer from acute
psychosis, particularly on high doses of some strains of cannabis. But, as a
general rule, cannabis is safer than the opioid-based pain medications.
Although opioids can provide much-needed pain relief for dying patients, the
drugs often cause unpleasant side effects such as severe constipation and
sedation, Juurlink
says. “And very often they just don’t work that well,” he adds.
Many patients will develop tolerance to opioids with regular use. That means
it takes a higher and higher dose to achieve the same effect. At very high
doses, “opioids can paradoxically make pain worse,” Juurlink says. This intensification of pain is
called opioid-induced
hyperalgesia and it appears to result
from the activity of these drugs on certain receptors in the brain that make
patients hypersensitive to stimuli.
To make matters worse, prolonged use of an opioid leads to a physical
dependence on the drug. Stopping the medication abruptly can trigger withdrawal
symptoms such as diarrhea and abdominal pain.
For all these reasons, it’s certainly worthwhile considering cannabis as an
alternative to opioids for palliative-care patients.
Maida says
it’s important for patients to know that medical cannabis is not the same as
recreational marijuana.
Medical cannabis is produced by companies that are licensed and regulated by
Health Canada. The controlled cannabis products contain specific ratios of two
medically active compounds – tetrahydrocannabinol (THC) and cannabidiol (CBD) which each have different
effects on patients. The dried plant material is also free of pesticides, mould
and other impurities.
The same cannot be said for recreational pot, which can
differ widely in intensity and may contain contaminants.
Maida says
it’s hard to predict if an individual patient will actually benefit from
cannabis. “There is a lot of variation in response.” He will often suggest that
patients try two strains containing different levels of THC and CBD to see what
might work. “The selection process involves a bit of trial and error.”
With this background in mind, let’s now return to your original question: How
does your father get access to medical marijuana?
Maida says
your father should ask his doctor for a referral to another physician who is
willing to authorize its use. “If a doctor doesn’t know the science behind
prescribing medical marijuana, there are others who have that experience.”
He points out that the referral process is used in other situations where
physicians may have a personal objection to a certain treatment.
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